Clemson Tigers at Syracuse Orange odds, picks and best bets

The defending-champion Clemson Tigers (2-0, No. 1 in the nation) visit the unranked Syracuse Orange (1-1) Saturday at Carrier Dome in Syracuse, NY in an ACC showdown. Kickoff is scheduled for 7:30 p.m. ET.

Syracuse has fallen out of the top 25 in the Amway Coaches Poll powered by USA TODAY Sports; they were previously ranked No. 22 in the nation.

Clemson Tigers at Syracuse Orange: Betting trends and tips

  • Clemson breezed past Georgia Tech 52-14 in the season opener before a much tighter 24-10 victory over 16th-ranked Texas A&M last Saturday.
  • Syracuse opened the year with a quality 24-0 shutout of Liberty but took an ugly 63-20 loss at No. 21 Maryland last weekend.
  • Tigers QB Trevor Lawrence has completed 37 of 58 passing attempts for 436 yards, but has just two touchdowns against three interceptions.
  • RB Travis Etienne has carried the ball 28 times for 258 yards and three scores.
  • Syracuse QB Tommy DeVito has passed for 506 yards and three touchdowns with three picks through two games. RB Moe Neal has 136 yards and a touchdown on the ground.

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  • Clemson is up 5-2 in the all-time head-to-head series, taking last year’s meeting 27-23 at home. The Orange won by a field goal (27-24) in 2017.
  • The largest win in the series was a 54-0 Clemson drubbing of Syracuse in 2016.
  • Both schools are 1-1 against the spread this season.
  • They’re also both 1-1 against the over/under. Each side has averaged more than 10 fewer points than the projected total.
  • Syracuse was 7-6 against the over/under last year, finishing an average of 0.2 points above the projection. Clemson went 7-8 against the number, but finished an average of 0.9 points above the projection.
  • Syracuse went 4-1-1 against the spread at home last season, covering by an average of 8.3 points.
  • The Tigers were 4-1 as the visitors last season, covering by 15 points on average.

Clemson at Syracuse: Odds, betting lines and picks

Sep 7, 2019; Clemson, SC, USA; Clemson Tigers running back Lyn-J Dixon (23) celebrates with wide receivers Joseph Ngata (10) and Tee Higgins (5) during the second half of the game against the Texas A&M Aggies at Clemson Memorial Stadium. Mandatory Credit: Joshua S. Kelly-USA TODAY Sports

Photo Credit: Joshua S. Kelly – USA TODAY Sports

Odds provided by BetMGM ; for a full-set of sports betting odds , access them at USA TODAY Sports .Lines last updated Thursday at 5 p.m. ET.


Clemson 42, Syracuse 20

Moneyline ( ?)

The moneyline was off the board (OTB) at time of posting. That’s okay. We’re not going to worry about betting the outright for the No. 1 team in the nation against an unranked opponent.

Against the Spread ( ?)

Things get a lot more interesting on the spread with the Tigers favored by -27.5 (-115). Lawrence has been largely unimpressive to start the season; however, and the Orange has played Clemson quite tight in their conference rivalry (with the exception of the 2016 blowout). Back Syracuse at + 27.5 (-106).

Over/Under ( ?)

The total will be tight in this one. The Clemson offense stumbled last week against a strong Texas A&M defense, but the Orange gave up a 60 burger to Maryland a week ago. Lean ever so slightly to the UNDER (62.5, -110) as Syracuse covers.

Get some action in this one by placing a bet at BetMGM. Want more sports betting coverage and tips? Visit us at

Esten’s college football record: 0-3

Follow Esten on Twitter @EstenMcLaren and @SportsbookWire.


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