Tylex: instructions for use
Tylex CD tabletas is a combination drug that contains Paracetamol and Codeine.
The mechanism of antipyretic action of paracetamol is due to the ability to influence the central nervous system by blocking the synthesis of its prostaglandins. This effect is possible due to its ability to inhibit cyclooxygenase 1 and 2. It also affects the centers in the CNS, which are responsible for the thermoregulatory and pain centers. Paracetamol has no anti-inflammatory effect. As a consequence, the drug has no effect on the state of water-salt balance, as well as the mucous surface in the gastrointestinal tract.
Mexican Codeine belongs to the opioid group of drugs. It has the property of a myorelaxant and a mild narcotic analgesic. Its main property used in treatment of flu and cold is the ability to suppress cough centers in CNS for a short time. When used in small doses, it increases the effect of paracetamol.
The drug can be ordered from the online pharmacy medicinesmexicorx information about availability and price is available to the patient.
Indications for use of the Tylex medicine
The drug is intended for short-term treatment of medium-intensity pain that does not subside after taking non-steroidal anti-inflammatory drugs (paracetamol, ibuprofen, acetylsalicylic acid).
Migraine-like headache;
menstrual pain in women;
toothache;
Neuralgia;
muscle pains;
joint pains;
low back pain;
Acute respiratory viral illnesses with sinusitis and elevated body temperature;
dry unproductive cough;
rheumatic pain.
If after taking Tylex the pain syndrome does not stop, or on the contrary increases and lasts more than 3 days, it is necessary to consult a specialist.
Dosing regimen
According to the instructions, the drug should be taken 1–2 tablets at an interval of 4–6 hours. Tylex medicine is not used by persons under the age of majority. The product is taken orally, without chewing and wash down with plenty of liquid.
The course of the drug should start with the minimum allowable dosage, and in the absence of effect it increases. Tylex should not take more than 3 days without expert advice.
Contraindications
Do not recommend receiving Tylex in the following cases:
Increased individual sensitivity to the components of the drug (Codeine, Paracetamol).
Diseases of the Hepatobiliary and urinary systems.
Acute respiratory function impairment.
Chronic obstructive pulmonary disease.
Bronchial asthma (attack).
Hereditary increase in bilirubin levels.
Enzyme deficiency of glucose-6-phosphate dehydrogenase.
Blood diseases.
Crash and conditions associated with increased intracranial pressure.
Alcohol addiction.
Addiction to narcotic drugs.
Diseases of the gastrointestinal tract, which are accompanied by inhibition of peristalsis or increased gas formation.
Dynamic disorders of intestinal patency.
Due to the suppression of respiratory function as well as increased intracranial pressure, Codeine also affects the pupil response.
If a patient has severe liver damage due to alcohol dependence, even minimal doses of Tylex medicine can cause an overdose.
Before you start using the drug Tylex, it is necessary to get a consultation with a specialist. Patients with arthritic joint damage, as well as those who regularly take drugs from the group of anticoagulants like Heparin, Warfarin, and others, should be especially careful.
Side effects
If the drug is taken in permissible dosages, the occurrence of side effects is practically impossible. If the patient’s condition worsens, however, it is necessary to consult a physician.
Respiratory system: bronchial spasm (especially in patients with hypersensitivity to aspirin or other drugs from the group of non-steroidal anti-inflammatory drugs).
Urinary system disorders: presence of pus in urine.
Psychiatric disorders: depressive episodes; hallucinations; nightmares; anxiety; impairment of consciousness; psycho-emotional disturbances such as euphoria and dysphoria.
Nervous system disorders: increased somnolence; dizziness; distraction of attention.
Visual system disorders: miosis; photophobia; blurred visual acuity (blurred pictures and blurred contours of objects).
Hearing apparatus disorders: hearing loss; dizziness.
Cardiovascular system disorders: Increased heart rate; heart pain.
Decrease in blood pressure.
Musculoskeletal system disorders: muscle soreness;
With increasing dosage: increase in muscle tone.
Medicines containing Paracetamol should not be combined with other medicines containing the same active ingredient in order to prevent overdose.
Codeine in Mexico is addictive and tolerant, leading to increased anxiety, irritability after treatment.
Overdose
Tylex overdose is increased when alcohol is combined with psychotropic substances.
Manifestation of overdose during the first day: nausea followed by vomiting, decreased appetite and abdominal pain, pale skin. Symptoms associated with Hepatobiliary system damage occur after 12–48 hours. There is a violation of glucose metabolism and acid-base balance disorder of the type of metabolic acidosis.
When overdosing with Paracetamol (Mexico) occurs liver dysfunction and may lead to liver failure, blood clotting disorders, lowering of blood glucose levels to pathological, as well as, in the worst case, to coma with subsequent death.
Acute renal failure with damage to the renal tubules is manifested by pain in the lumbar region, excretion of blood with urine, the presence of protein in the urine.
Taking into account the fact that the drug contains Codeine, the following effects are possible as a result of its overdose:
central nervous system depression;
respiratory impairment, occurring mainly due to simultaneous use of sedatives or alcohol in inadmissible dosages;
miosis;
nausea followed by vomiting, as well as painful sensations in the epigastric region;
abnormal lowering of blood pressure and increased heart rate.
Increased doses of Codeine (Mexico) lead to a status soporosus or, conversely, excessive emotionality. Seizures are common in children.
Treatment: symptomatic treatment to maintain respiratory function and control vital signs until the condition normalizes. If less than one hour has elapsed since the administration of Codeine to adults in doses greater than 350 mg, and in children at a rate of 5 mg per kg of body weight, it is advisable to take sorbents such as activated charcoal. If respiratory function is impaired or coma occurs, the antidote Naloxone should be used. Monitor the patient’s condition for 4 hours after administering Naloxone, or for about 8 hours if prolonged-acting Naloxone was administered.
Interaction
During the treatment with the drug Tylex, you should be careful with drugs containing Paracetamol, as well as mucolytics.
Increases the effect of anticoagulants, which leads to the development of undesirable adverse reactions.
Mexican Codeine together with ethanol affects psychomotor processes.
Groups of drugs related to microsomal oxidation inhibitors such as anti-tuberculosis drugs, barbiturates, antiepileptics, and ethanol increase the negative effect on the liver.
Administration of Tylex with MAO inhibitors leads to cerebellar ataxia, decreased blood pressure, accommodation spasm, and sensory disturbances in the form of paresthesias.
Drugs that have a depressing effect on the central nervous system, respiratory system, as well as a pronounced sedative effect.
Oral contraceptives reduce the rate of metabolism by 20-30%. Long-term use of drugs with anticonvulsants reduces the effectiveness of Paracetamol.
More detailed information about this medicine can be found in the instructions accompanying the package by the manufacturer. The information on this website is for information purposes only.